Multiple psychological factors predict abdominal pain severity in children with irritable bowel syndrome.

ABSTRACT:

Background

Anxiety and depression are implicated as contributors to abdominal pain in pediatric irritable bowel syndrome (IBS) but is unclear if this pain is associated with other psychological factors. The study objective was to test if the impact of anxiety or depression on IBS symptom severity is mediated by somatization and/or pain catastrophizing.

Methods

We utilized baseline data from local pediatric IBS clinical studies. Through mediation analysis, we assessed whether somatization or pain catastrophizing mediated (either independently or combined) the separate relationships of anxiety or depression with IBS abdominal pain severity.

Key results

We analyzed 261 participants. All psychological factors were positively correlated with one another and IBS abdominal p

SUBMITTER: Hollier JM 

PROVIDER: S-EPMC6651721 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature