PM_2.5 Filter Extraction Methods: Implications for Chemical and Toxicological Analyses.

ABSTRACT: Toxicology research into the global public health burden of fine particulate matter (PM_2.5) exposures frequently requires extraction of PM_2.5 from filters. A standardized method for these extractions does not exist, leading to inaccurate interlaboratory comparisons. It is largely unknown how different filter extraction methods might impact the composition and bioactivity of the resulting samples. We characterized the variation in these metrics by using equal portions of a single PM_2.5 filter, with each portion undergoing a different extraction method. Significant differences were observed between extraction methods for concentrations of elements and polycyclic aromatic hydrocarbons (PAHs) for the PM_2.5 tested following its preparation for biologi

SUBMITTER: Roper C 

PROVIDER: S-EPMC6652177 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature