Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.

ABSTRACT:

Objective

To investigate whether the genetic burden of type 2 diabetes modifies the association between the quality of dietary fat and the incidence of type 2 diabetes.

Design

Individual participant data meta-analysis.

Data sources

Eligible prospective cohort studies were systematically sourced from studies published between January 1970 and February 2017 through electronic searches in major medical databases (Medline, Embase, and Scopus) and discussion with investigators.

Review methods

Data from cohort studies or multicohort consortia with available genome-wide genetic data and information about the quality of dietary fat and the incidence of type 2 diabetes in participants of European descent was sought. Prospective cohorts that had accrued five or more year

SUBMITTER: Merino J 

PROVIDER: S-EPMC6652797 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature