Seizure burden pre- and postresection of low-grade gliomas as a predictor of tumor progression in low-grade gliomas.

ABSTRACT:

Background

Low-grade gliomas (LGGs) are slow-growing, infiltrative tumors frequently associated with seizures. Predicting which patients will develop early tumor recurrence based on clinical indicators following initial surgical intervention remains a challenge. Seizure recurrence following surgery may be an early indicator of tumor recurrence, especially in patients presenting with increase in seizure frequency.

Methods

This study analyzed 148 patients meeting inclusion criteria (age >18 years, LGG diagnosis, at least 1 seizure event recorded before and after initial surgical intervention). All patients were treated at the Brain and Spine Center at The University of Texas MD Anderson Cancer Center from January 2000 to March 2013. Seizure frequency in a 6-month period before

SUBMITTER: Santos-Pinheiro F 

PROVIDER: S-EPMC6656314 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature