Relevance of Multi-Omics Studies in Cardiovascular Diseases.

ABSTRACT: Cardiovascular diseases are the leading cause of death around the world. Despite the larger number of genes and loci identified, the precise mechanisms by which these genes influence risk of cardiovascular disease is not well understood. Recent advances in the development and optimization of high-throughput technologies for the generation of "omics data" have provided a deeper understanding of the processes and dynamic interactions involved in human diseases. However, the integrative analysis of "omics" data is not straightforward and represents several logistic and computational challenges. In spite of these difficulties, several studies have successfully applied integrative genomics approaches for the investigation of novel mechanisms and plasma biomarkers involved in cardiovascular dise

SUBMITTER: Leon-Mimila P 

PROVIDER: S-EPMC6656333 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature