Depressive Symptom Profiles and Survival in Older Patients with Cancer: Latent Class Analysis of the ELCAPA Cohort Study.

ABSTRACT:

Background

The expression of depressive symptoms in older people with cancer is heterogeneous because of specific features of age or cancer comorbidity. We aimed to identify depressive symptom profiles in this population and describe the associated features including survival.

Materials and methods

Patients ≥70 years who were referred to geriatric oncology clinics were prospectively included in the ELCAPA study. In this subanalysis, depressive symptoms were used as indicators in a latent class analysis. Multinomial multivariable logistic regression and Cox models examined the association of each class with baseline characteristics and mortality.

Results

For the 847 complete-case patients included (median age, 79 years; interquartile range, 76-84; women, 47.9%), we ide

SUBMITTER: Gouraud C 

PROVIDER: S-EPMC6656460 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature