Outcomes of liver transplantation for non-alcoholic steatohepatitis: A European Liver Transplant Registry study.

ABSTRACT:

Background & aims

Little is known about outcomes of liver transplantation for patients with non-alcoholic steatohepatitis (NASH). We aimed to determine the frequency and outcomes of liver transplantation for patients with NASH in Europe and identify prognostic factors.

Methods

We analysed data from patients transplanted for end-stage liver disease between January 2002 and December 2016 using the European Liver Transplant Registry database. We compared data between patients with NASH versus other aetiologies. The principle endpoints were patient and overall allograft survival.

Results

Among 68,950 adults undergoing first liver transplantation, 4.0% were transplanted for NASH - an increase from 1.2% in 2002 to 8.4% in 2016. A greater proportion of patients transplanted

SUBMITTER: Haldar D 

PROVIDER: S-EPMC6656693 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature