Statin use and the risk of ovarian and endometrial cancers: a meta-analysis.

ABSTRACT:

Background

The relationship between statin use and the risk of ovarian or endometrial cancer remains controversial. Here, we investigated the relationship between statin use and the risk of ovarian and endometrial cancers.

Methods

We conducted a meta-analysis using articles retrieved from the PubMed, Embase, and Web of Science databases. All original comparative studies published in English that were related to statin use and the risk of ovarian or endometrial cancer were included.

Results

This meta-analysis included 19 studies enrolling 1,999,362 female subjects and 19,849 cancer cases (7,948 ovarian cancer cases and 11,901 endometrial cancer cases). The overall analysis indicated that statin use did not significantly reduce the risk of ovarian cancer [relative risk

SUBMITTER: Wang Y 

PROVIDER: S-EPMC6657066 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature