Association between serum visfatin levels and atherosclerotic plaque in patients with type 2 diabetes.

ABSTRACT:

Background

Visfatin is a multifaceted protein that plays an important role in regulating a variety of physiological and pathological processes, including obesity, diabetes and cardiovascular disease. However, circulating visfatin levels in atherosclerosis plaque progression in patients with type 2 diabetes, or its association with the vascular territory affected remain unclear.

Methods

We evaluated the relationship between visfatin levels and carotid or femoral artery atherosclerosis in Chinese patients with type 2 diabetes. Serum levels of visfatin were measured by enzyme-linked immunosorbent assay (ELISA) in 97 inpatients with type 2 diabetes. Carotid and/or femoral atherosclerotic plaques were detected by B-mode ultrasound.

Results

Serum visfatin levels were elevat

SUBMITTER: Zheng LY 

PROVIDER: S-EPMC6657107 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature