Weak association between the interleukin-8 rs4073 polymorphism and acute pancreatitis: a cumulative meta-analysis.

ABSTRACT:

Background

Several studies have been performed to investigate the associations between interleukin (IL)-8 rs4073 polymorphism and acute pancreatitis (AP), but the results are inconclusive. We conducted this cumulative meta-analysis for a precise estimate of the relationship between IL-8 rs4073 polymorphism and acute pancreatitis.

Methods

We searched the electronic databases for relevant studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to evaluate the strength of the associations. For a better presentation of how the pooled ORs changed as updated evidence accumulated, we used forest plots from a cumulative meta-analysis method.

Results

Ten studies involving 1646 AP patients and 1816 controls were finally included in this meta-analysis. Cumu

SUBMITTER: Li Y 

PROVIDER: S-EPMC6657145 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature