Negative tuberculin skin test result predicts all-cause mortality among tuberculosis patients with HIV and diabetes comorbidity.

ABSTRACT:

Purpose

The purpose of this study was to determine if a negative tuberculin skin test (TST) result is associated with increased risk of mortality during tuberculosis (TB) treatment.

Methods

We conducted a retrospective cohort study among patients aged ≥15 years with culture-positive TB reported to the Georgia State Electronic Notifiable Disease Surveillance System from 2009 to 2014. TST positivity was defined by the US Centers for Disease Control guidelines. All-cause mortality during TB treatment as well as HIV, diabetes, and end-stage renal disease status were collected from surveillance data. Log-binomial regression was used to estimate adjusted risk ratios and 95% confidence intervals.

Results

Among 1186 culture-confirmed TB patients, 780 (65.8%) with a valid TST

SUBMITTER: Salindri AD 

PROVIDER: S-EPMC6657345 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature