Confocal-Assisted Multispectral Fluorescent Microscopy for Brain Tumor Surgery.

ABSTRACT: Optimal surgical therapy for brain tumors is the combination of complete resection with minimal invasion and damage to the adjacent normal tissue. To achieve this goal, we need advanced imaging techniques on a scale from macro- to microscopic resolution. In the last decade, the development of fluorescence-guided surgery has been the most influential breakthrough, marginally improving outcomes in brain tumor surgery. Multispectral fluorescence microscopy (MFL) is a novel imaging technique that allows the overlapping of a fluorescent image and a white light image in real-time, with delivery of the merged image to the surgeon through the eyepieces of a surgical microscope. MFL permits the detection and characterization of brain tumors using fluorescent molecular markers such as 5-aminolevulin

SUBMITTER: Charalampaki P 

PROVIDER: S-EPMC6657348 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature