Main histological parameters to be evaluated in an experimental model of myocardial infarct treated by stem cells on pigs.

ABSTRACT: Myocardial infarction has been carefully studied in numerous experimental models. Most of these models are based on electrophysiological and functional data, and pay less attention to histological discoveries. During the last decade, treatment using advanced therapies, mainly cell therapy, has prevailed from among all the options to be studied for treating myocardial infarction. In our study we wanted to show the fundamental histological parameters to be evaluated during the development of an infarction on an experimental model as well as treatment with mesenchymal stem cells derived from adipose tissue applied intra-lesionally. The fundamental parameters to study in infarcted tissue at the histological level are the cells involved in the inflammatory process (lymphocytes, macrophages and

SUBMITTER: Garcia Gomez-Heras S 

PROVIDER: S-EPMC6657680 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature