ParaDB: A manually curated database containing genomic annotation for the human pathogenic fungi Paracoccidioides spp.

ABSTRACT:

Background

The genus Paracoccidioides consists of thermodymorphic fungi responsible for Paracoccidioidomycosis (PCM), a systemic mycosis that has been registered to affect ~10 million people in Latin America. Biogeographical data subdivided the genus Paracoccidioides in five divergent subgroups, which have been recently classified as different species. Genomic sequencing of five Paracoccidioides isolates, representing each of these subgroups/species provided an important framework for the development of post-genomic studies with these fungi. However, functional annotations of these genomes have not been submitted to manual curation and, as a result, ~60-90% of the Paracoccidioides protein-coding genes (depending on isolate/annotation) are currently described as responsible for hypo

SUBMITTER: Aciole Barbosa D 

PROVIDER: S-EPMC6658007 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature