Exact distance measurements for structure and dynamics in solid proteins by fast-magic-angle-spinning NMR.

ABSTRACT: Fast-magic-angle-spinning solid-state NMR is a developing technique for determination of protein structure and dynamics. Proton-proton correlations usually lead to rough distance restraints, a serious hurdle towards high-resolution structures. Analogous to the "eNOE" concept in solution, an integrative approach for more accurate restraints enables improved structural accuracy with minimal analytical effort.

SUBMITTER: Grohe K 

PROVIDER: S-EPMC6658100 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature