Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study.

ABSTRACT:

Background

Quantifying reproducibility of native T1 and T2 mapping over a long period (> 1 year) is necessary to assess whether changes in T1 and T2 over repeated sessions in a longitudinal study are associated with variability due to underlying tissue composition or technical confounders.

Objectives

To carry out a single-center phantom study to 1) investigate measurement reproducibility of slice-interleaved T1 (STONE) and T2 mapping over 20 months, 2) quantify sources of variability, and 3) compare reproducibility and measurements against reference spin-echo measurements.

Methods

MR imaging was performed on a 1.5 Tesla Philips Achieva scanner every 2-3 weeks over 20 months using the T1MES phantom. In each session, slice-interleaved T1 and T2 mapping was repeated 3 ti

SUBMITTER: Jang J 

PROVIDER: S-EPMC6658153 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature