Home environment: respiratory and allergic phenotypes from birth to age six in the PELAGIE cohort.

ABSTRACT: Childhood asthma and allergies are particularly prevalent diseases. Our objective is to identify respiratory and allergic phenotypes from birth to 6 years of age, and to explore their environmental determinants, especially those related to the home environment. Data on respiratory and allergic health outcomes and domestic environmental exposure were collected for 935 mother-infant pairs from a longitudinal mother-child cohort based on mothers, included before 19 weeks of gestation in Brittany between 2002 and 2006. Information was obtained by self-administered questionnaires completed by parents at inclusion, delivery, and when the child was 2 and 6 years old. Kml3D clustering was used to describe profiles of children who shared similar trajectories of symptoms as phenotypes. Association w

SUBMITTER: Apel K 

PROVIDER: S-EPMC6658488 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature