Catastrophizing Interferes with Cognitive Modulation of Pain in Women with Fibromyalgia.

ABSTRACT:

Background

Pain modulation is a critical function of the nociceptive system that includes the ability to engage descending pain control systems to maintain a functional balance between facilitation and inhibition of incoming sensory stimuli. Dysfunctional pain modulation is associated with increased risk for chronic pain and is characteristic of fibromyalgia (FM). Catastrophizing is also common in FM. However, its influence on pain modulation is poorly understood.

Objective

To determine the role of catastrophizing on central nervous system processing during pain modulation in FM via examining brain responses and pain sensitivity during an attention-distraction paradigm.

Methods

Twenty FM patients and 18 healthy controls (CO) underwent functional magnetic resonance ima

SUBMITTER: Ellingson LD 

PROVIDER: S-EPMC6659027 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature