Early prolonged ambulatory cardiac monitoring in stroke (EPACS): an open-label randomised controlled trial.

ABSTRACT:

Background

Cardioembolism in paroxysmal atrial fibrillation (PAF) is a preventable cause of transient ischaemic attack (TIA) or ischaemic stroke; however, due to its transient nature, a short-duration Holter monitor may miss a significant proportion of events.

Methods

We conducted an open-label randomised controlled trial of cardiac monitoring after a TIA or ischaemic stroke comparing a 14-day ECG monitoring patch (Zio^® Patch, iRhythm Technologies) with short-duration Holter monitoring for the detection of PAF. The primary outcome was the detection of one or more episodes of ECG-documented PAF lasting at least 30 s within 90 days in each of the study arms. A budget impact analysis from the healthcare perspective was performed.

Results

From February 2016 thr

SUBMITTER: Kaura A 

PROVIDER: S-EPMC6659210 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature