Effects of an over-the-counter lactic-acid containing intra-vaginal douching product on the vaginal microbiota.

ABSTRACT:

Background

Over-the-counter intra-vaginal lactic-acid containing douches are marketed as vaginal hygiene products that support optimal vaginal pH balance. We report the effect of a commercially available douche (Etos®) on the vaginal microbiota (VM) in a prospective study.

Results

Twenty-five healthy women were recruited through advertisements in 2015-2017 (ethical approval: METC-2014_413) and followed over three menstrual cycles. The participants had a median age of 24 years [IQR: 22-29], were mostly Dutch-Caucasian (88%), and 60% used combined oral contraceptives. All participants douched three times a week during the second cycle, starting on the first day of that cycle. Participants completed a questionnaire at baseline, kept a daily diary to report douching, menses, and

SUBMITTER: van der Veer C 

PROVIDER: S-EPMC6659218 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature