The role of commensal microbes in the lifespan of Drosophila melanogaster.

ABSTRACT: Commensal microbes have mutualistic relationships with their host and mainly live in the host intestine. There are many studies on the relationships between commensal microbes and host physiology. However, there are inconsistent results on the effects of commensal microbes on host lifespan. To clarify this controversy, we generated axenic flies by using two controlled methods - bleaching and antibiotic treatment - and investigated the relationship between the commensal microbes and host lifespan in Drosophila melanogaster. The removal of microbes by using bleaching and antibiotic treatments without detrimental effects increased fly lifespan. Furthermore, a strain of flies colonized with a high load of microbiota showed a greater effect on lifespan extension when the microbes were el

SUBMITTER: Lee HY 

PROVIDER: S-EPMC6660043 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature