Gastric cancer in patients with gastric atrophy and intestinal metaplasia: A systematic review and meta-analysis.

ABSTRACT:

Aim

Intestinal metaplasia (IM) and gastric atrophy (GA) are precancerous lesions in the stomach. There is a large debate on natural course of these lesions and surveillance strategy in these patients. This meta-analysis was aimed to find the most appropriate follow up and the rate of progression from IM and GA to GC.

Methods

This meta-analysis is followed and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Electronic databases including EMBASE, PubMed, Web of Science databases, Scopus, and the Cochrane Library were searched until July 2018. Cochran's Q test and I-square (I2) test were used to examine heterogeneity across included studies. We pooled data using random-effect or fixed effect models indicated as i

SUBMITTER: Akbari M 

PROVIDER: S-EPMC6660080 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature