Antenatal active maternal asthma and other atopic disorders is associated with ADHD behaviors among school-aged children.

ABSTRACT:

Background

Identifying modifiable risk factors for neuropsychological correlates of attention deficit hyperactivity disorder (ADHD) in early childhood can inform prevention strategies. Prenatal inflammatory states, such as maternal asthma and other atopic disorders, have been increasingly linked to enhanced risk for neurobehavioral disorders in children, with some studies suggesting sex-specific effects.

Objectives

To assess the association between maternal active asthma and/or atopy in the antenatal period and child symptoms of ADHD during mid-childhood and, given the male-bias in ADHD prevalence, to examine modifying effects of child sex.

Study design

The study sample includes 250 maternal-child pairs enrolled in the Boston-based Asthma Coalition on Community, Envir

SUBMITTER: Cowell WJ 

PROVIDER: S-EPMC6660383 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature