Persistence with dual antiplatelet therapy after percutaneous coronary intervention for ST-segment elevation acute coronary syndrome: a population-based cohort study in Catalonia (Spain).

ABSTRACT:

Objectives

Guidelines recommending 12-month dual antiplatelet therapy (DAPT) in patients with ST-elevation acute coronary syndrome (STEACS) undergoing percutaneous coronary intervention (PCI) were published in year 2012. We aimed to describe the influence of guideline implementation on the trend in 12-month persistence with DAPT between 2010 and 2015 and to evaluate its relationship with DAPT duration regimens recommended at discharge from PCI hospitals.

Design

Observational study based on region-wide registry data linked to pharmacy billing data for DAPT follow-up.

Setting

All PCI hospitals (10) belonging to the acute myocardial infarction (AMI) code network in Catalonia (Spain).

Participants

10 711 STEACS patients undergoing PCI between 2010 and 2015 were fol

SUBMITTER: Ribera A 

PROVIDER: S-EPMC6661631 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature