The association of stillbirth with placental abnormalities in growth-restricted and normally grown fetuses.

ABSTRACT:

Background

Stillbirth, defined as foetal death ≥20 weeks' gestation, is associated with poor foetal growth and is often attributed to placental abnormalities, which are also associated with poor foetal growth. Evaluating inter-relationships between placental abnormalities, poor foetal growth, and stillbirth may improve our understanding of the underlying mechanisms for some causes of stillbirth.

Objective

Our primary objective was to determine whether poor foetal growth, operationalised as small for gestational age (SGA), mediates the relationship between placental abnormalities and stillbirth.

Methods

We used data from the Stillbirth Collaborative Research Network study, a population-based case-control study conducted from 2006-2008. Our analysis included 266 stillbi

SUBMITTER: Freedman AA 

PROVIDER: S-EPMC6662619 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature