Red fox genome assembly identifies genomic regions associated with tame and aggressive behaviours.

ABSTRACT: Strains of red fox (Vulpes vulpes) with markedly different behavioural phenotypes have been developed in the famous long-term selective breeding programme known as the Russian farm-fox experiment. Here we sequenced and assembled the red fox genome and re-sequenced a subset of foxes from the tame, aggressive and conventional farm-bred populations to identify genomic regions associated with the response to selection for behaviour. Analysis of the re-sequenced genomes identified 103 regions with either significantly decreased heterozygosity in one of the three populations or increased divergence between the populations. A strong positional candidate gene for tame behaviour was highlighted: SorCS1, which encodes the main trafficking protein for AMPA glutamate receptors and neurexins and sugges

SUBMITTER: Kukekova AV 

PROVIDER: S-EPMC6663081 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature