N-of-1 Clinical Trials in Nutritional Interventions Directed at Improving Cognitive Function.

ABSTRACT: Longer life expectancy has led to an increase in the prevalence of age-related cognitive decline and dementia worldwide. Due to the current lack of effective treatment for these conditions, preventive strategies represent a research priority. A large body of evidence suggests that nutrition is involved in the pathogenesis of age-related cognitive decline, but also that it may play a critical role in slowing down its progression. At a population level, healthy dietary patterns interventions, such as the Mediterranean and the MIND diets, have been associated with improved cognitive performance and a decreased risk of neurodegenerative disease development. In the era of evidence-based medicine and patient-centered healthcare, personalized nutritional recommendations would offer a considerable

SUBMITTER: Soldevila-Domenech N 

PROVIDER: S-EPMC6663977 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature