Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study.

ABSTRACT:

Objectives

To examine the association between the Life Simple 7 cardiovascular health score at age 50 and incidence of dementia.

Design

Prospective cohort study.

Setting

Civil service departments in London (Whitehall II study; study inception 1985-88).

Participants

7899 participants with data on the cardiovascular health score at age 50.

Exposures

The cardiovascular health score included four behavioural (smoking, diet, physical activity, body mass index) and three biological (fasting glucose, blood cholesterol, blood pressure) metrics, coded on a three point scale (0, 1, 2). The cardiovascular health score was the sum of seven metrics (score range 0-14) and was categorised into poor (scores 0-6), intermediate (7-11), and optimal (12-14) cardiovascular h

SUBMITTER: Sabia S 

PROVIDER: S-EPMC6664261 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature