Prior Appendectomy and the Onset and Course of Crohn's Disease in Chinese Patients.

ABSTRACT:

Background and aim

The relationship between prior appendectomy and Crohn's disease (CD) has previously revealed conflicting findings. The present study investigates the relationship between prior appendectomy and CD development in Chinese patients.

Methods

A retrospective case-control study was performed to compare prior appendectomy rate between CD patients and age- and gender-matched controls at two Chinese hospitals. The clinical course of CD was determined in patients who underwent and did not undergo appendectomies before CD diagnosis.

Results

A total of 617 CD patients and 617 controls were included. The appendectomy rate before CD diagnosis in patients was higher, when compared to controls (6.65% versus 3.73%, P = 0.033). Appendectomy was a risk factor f

SUBMITTER: Chen D 

PROVIDER: S-EPMC6664542 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature