Preeclampsia and risk of end stage kidney disease: A Swedish nationwide cohort study.

ABSTRACT:

Background

Preeclampsia has been suggested to increase the risk of end-stage kidney disease (ESKD); however, most studies were unable to adjust for potential confounders including pre-existing comorbidities such as renal disease and cardiovascular disease (CVD). We aimed to examine the association between preeclampsia and the risk of ESKD in healthy women, while taking into account pre-existing comorbidity and potential confounders.

Methods and findings

Using data from the Swedish Medical Birth Register (MBR), women who had singleton live births in Sweden between 1982 and 2012, including those who had preeclampsia, were identified. Women with a diagnosis of chronic kidney disease (CKD), CVD, hypertension, or diabetes prior to the first pregnancy were excluded. The outcome wa

SUBMITTER: Khashan AS 

PROVIDER: S-EPMC6667103 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature