Intensive follow-up strategies after radical surgery for nonmetastatic colorectal cancer: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Intensive follow-up after surgery for colorectal cancers is common in clinical practice, but evidence of a survival benefit is limited.

Objective

To conduct a systematic review and meta-analysis on the effects of follow-up strategies for nonmetastatic colorectal cancer.

Data sources

We searched Medline, Embase, and CENTRAL databases through May 30, 2018.

Study selection

We included randomized clinical trials evaluating intensive follow-up versus less follow-up in patients with nonmetastatic colorectal cancer.

Interventions

Intensive follow-up.

Main outcomes measures

Overall survival.

Results

The analyses included 17 trials with a total of 8039 patients. Compared with less follow-up, intensive follow-up significantly improved over

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC6667274 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature