Relationship between semiquantitative ¹⁸F-fluorodeoxyglucose positron emission tomography metrics and necrosis in classical Hodgkin lymphoma.

ABSTRACT: Semiquantitative ¹⁸F-fluoro-2-deoxy-D-glucose positron emission tomography (¹⁸F-FDG PET) parameters have been proposed as prognostic markers in classical Hodgkin lymphoma (cHL). In non-Hodgkin lymphoma necrosis as assessed by ¹⁸F-FDG PET or computed tomography (CT) (necrosis^visual) correlates with an adverse prognosis. We investigated whether semiquantitative ¹⁸F-FDG PET metrics correlate with necrosis^visual, determined the incidence of necrosis^visual and explored the prognostic impact of these factors in cHL. From 87 cHL cases treated with ABVD, (escalated) BEACOPP or CHOP chemotherapy between 2010 and 2017, 71 had both a NEDPAS/EARL accredited ¹⁸F-FDG PET and a contrast enhanced CT scan. Semiquantitat

SUBMITTER: Kahle XU 

PROVIDER: S-EPMC6667466 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature