Genetic structure and sex-biased gene flow in the history of southern African populations.

ABSTRACT:

Objectives

We investigated the genetic history of southern African populations with a special focus on their paternal history. We reexamined previous claims that the Y-chromosome haplogroup E1b1b (E-M293) was brought to southern Africa by pastoralists from eastern Africa, and investigated patterns of sex-biased gene flow in southern Africa.

Materials and methods

We analyzed previously published complete mtDNA genome sequences and ∼900 kb of NRY sequences from 23 populations from Namibia, Botswana, and Zambia, as well as haplogroup frequencies from a large sample of southern African populations and 23 newly genotyped Y-linked STR loci for samples assigned to haplogroup E1b1b.

Results

Our results support an eastern African origin for Y-chromosome haplogroup E1b1b (E-M29

SUBMITTER: Bajic V 

PROVIDER: S-EPMC6667921 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature