Deep RNA-Seq reveals miRNome differences in mammary tissue of lactating Holstein and Montbeliarde cows.

ABSTRACT:

Background

Genetic polymorphisms are known to influence milk production and composition. However, the genomic mechanisms involved in the genetic regulation of milk component synthesis are not completely understood. MicroRNAs (miRNAs) regulate gene expression. Previous research suggests that the high developmental potential of the mammary gland may depend in part on a specific miRNA expression pattern. The objective of the present study was to compare the mammary gland miRNomes of two dairy cow breeds, Holstein and Montbéliarde, which have different mammogenic potentials that are related to differences in dairy performance.

Results

Milk, fat, protein, and lactose yields were lower in Montbéliarde cows than in Holstein cows. We detected 754 distinct miRNAs in the mammary gland

SUBMITTER: Billa PA 

PROVIDER: S-EPMC6668132 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature