Utility of Biomarkers to Improve Prediction of Readmission or Mortality After Cardiac Surgery.

ABSTRACT:

Background

Hospital readmission within 30 days is associated with higher risks of complications, death, and increased costs. Accurate statistical models to stratify the risk of 30-day readmission or death after cardiac surgery could help clinical teams focus care on those patients at highest risk. We hypothesized biomarkers could improve prediction for readmission or mortality.

Methods

Levels of ST2, galectin-3, N-terminal pro-brain natriuretic peptide, cystatin C, interleukin-6, and interleukin-10 were measured in samples from 1,046 patients discharged after isolated coronary artery bypass graft surgery from eight medical centers, with external validation in 1,194 patients from five medical centers. Thirty-day readmission or mortality were ascertained using Medicare, state

SUBMITTER: Brown JR 

PROVIDER: S-EPMC6668355 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature