Higher vs. Lower DP for Ventilated Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

Driving pressure (DP) has recently become a promising mediator for the identification of the effects of mechanical ventilation on outcomes in acute respiratory distress syndrome (ARDS). The aim of this study was to systematically and quantitatively update and assess the association between DP and mortality among ventilated patients with ARDS.

Methods

PubMed, the Cochrane Library, ISI Web of Knowledge, and Embase were systematically searched from inception to June 2018. Two investigators conducted the literature search study selection, data extraction, and quality evaluation independently. RevMan 5.3 software was used for all statistical analyses.

Results

A total of seven studies comprising 8010 patients were included in this meta-analysis. Higher DP showed

SUBMITTER: Chen Z 

PROVIDER: S-EPMC6668539 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature