HIV infection and increased food insecurity are associated with adverse body composition changes among pregnant and lactating Kenyan women.

ABSTRACT:

Background/objectives

Body composition changes markedly during reproduction. In sub-Saharan Africa, impacts of HIV infection on body composition across pregnancy and lactation in the context of Option B+ antiretroviral therapy are unknown. Therefore, we sought to evaluate the role of HIV infection on body composition during pregnancy and lactation among Kenyan women.

Subjects/methods

A cohort of pregnant women (n = 333; 50.5% HIV+, receiving ART) were enrolled at seven clinics in western Kenya. Two prenatal (mean ± SD: 23.6 ± 4.4 and 33.4 ± 2.0 weeks gestation) and three postpartum (6, 14, and 36 weeks) measurements included: individual-level food insecurity, height, weight, fat mass (FM), and fat-free mass (FFM) by bioimpedance analysis (BIA), mid-upper arm circumference (M

SUBMITTER: Widen EM 

PROVIDER: S-EPMC6668710 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature