Comparison between liver transplantation and resection for hilar cholangiocarcinoma: A systematic review and meta-analysis.

ABSTRACT:

Background

Hilar cholangiocarcinoma (hCCA) is a rare and aggressive malignancy with R0 resection being currently the only option for long-term survival. With the improvement in the outcomes of liver transplantation (LT), the indications for LT have expanded to include other malignant tumors, such as hCCA. The aim of the present analysis is to demonstrate and critically evaluate the outcomes of LT compared to resection with curative intent in patients with hCCA.

Methods

We systematically searched the literature for articles published up to May 2018. The following algorithm was applied ((hilar cholangiocarcinoma) OR (perihilar cholangiocarcinoma) OR klatskin$ OR (bile duct neoplasm) OR cholangiocarcinoma) AND (transplant$ OR graft$).

Results

Neoadjuvant treatment with c

SUBMITTER: Moris D 

PROVIDER: S-EPMC6668826 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature