A population-based study of transdermal fentanyl initiation in Australian clinical practice.

ABSTRACT:

Purpose

Although guidelines caution against initiation of transdermal (TD) fentanyl among those who are opioid naïve, there is concern that not all people receive adequate prior opioid exposure. This study examined the percentage of people who are opioid naïve at the time of TD fentanyl initiation in Australia; strengths initiated; and characteristics associated with being opioid naïve.

Methods

This is a national retrospective cohort study derived from a 10% sample of Pharmaceutical Benefits Scheme concessional beneficiaries initiating TD fentanyl between 29 September 2009-31 December 2013. Individuals were deemed opioid naïve if they had no opioid dispensings in the previous 90 days. Logistic regression was used to determine characteristics associated with being opioid naïv

SUBMITTER: Gisev N 

PROVIDER: S-EPMC6669185 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature