The Mortality Burden of Multidrug-resistant Pathogens in India: A Retrospective, Observational Study.

ABSTRACT:

Background

The threat posed by antibiotic resistance is of increasing concern in low- and middle-income countries (LMICs) as their rates of antibiotic use increase. However, an understanding of the burden of resistance is lacking in LMICs, particularly for multidrug-resistant (MDR) pathogens.

Methods

We conducted a retrospective, 10-hospital study of the relationship between MDR pathogens and mortality in India. Patient-level antimicrobial susceptibility test (AST) results for Enterococcus spp., Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. were analyzed for their association with patient mortality outcomes.

Results

We analyzed data on 5103 AST results from 10 hospitals. The overa

SUBMITTER: Gandra S 

PROVIDER: S-EPMC6669283 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature