Biosynthetic Potential of a Novel Antarctic Actinobacterium Marisediminicola antarctica ZS314^T Revealed by Genomic Data Mining and Pigment Characterization.

ABSTRACT: Rare actinobacterial species are considered as potential resources of new natural products. Marisediminicola antarctica ZS314^T is the only type strain of the novel actinobacterial genus Marisediminicola isolated from intertidal sediments in East Antarctica. The strain ZS314^T was able to produce reddish orange pigments at low temperatures, showing characteristics of carotenoids. To understand the biosynthetic potential of this strain, the genome was completely sequenced for data mining. The complete genome had 3,352,609 base pairs (bp), much smaller than most genomes of actinomycetes. Five biosynthetic gene clusters (BGCs) were predicted in the genome, including a gene cluster responsible for the biosynthesis of C50 carotenoid, and four additional BGCs of

SUBMITTER: Liao L 

PROVIDER: S-EPMC6669644 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature