Predictors of asthma following severe respiratory syncytial virus (RSV) bronchiolitis in early childhood.

ABSTRACT:

Background

We sought to identify predictors of asthma development following severe early childhood RSV bronchiolitis. Different definitions of asthma were also compared.

Methods

This longitudinal, observational study (N = 343) followed patients (<2 years old) from a placebo-controlled trial (N = 979) of montelukast after RSV bronchiolitis to identify clinical, demographic, or biochemical predictors of asthma, atopic disorders, and chronic asthma therapy use at 6 years of age (Clinical Trials Registry Number: NCT01140048). Asthma (primary definition) was based on parental identification of wheeze at 6 AND 12 months before 6 years of age; definitions based on physician diagnosis as well as parental identification of wheeze at 6 OR 12 months (to consider seasonal effect) were a

SUBMITTER: Lu S 

PROVIDER: S-EPMC6669901 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature