High serum uric acid level is a mortality risk factor in peritoneal dialysis patients: a retrospective cohort study.

ABSTRACT:

Background

The results remain controversial with regards to the impact of serum uric acid on clinical outcomes from peritoneal dialysis population. The aim of our study was to investigate the influence of serum uric acid levels on mortality in peritoneal dialysis patients.

Methods

Data on 9405 peritoneal dialysis patients from the Zhejiang Renal Data system were retrospectively analyzed. All demographic and laboratory data were recorded at baseline. The study cohort was divided into quintiles according to baseline uric acid level (mg/dL): Q1 (< 6.06), Q2 (6.06-6.67), Q3 (6.68-7.27) (reference), Q4 (7.28-8.03), and Q5 (≥8.04). Hazards ratio (HR) of all-cause and cardiovascular mortality was calculated.

Results

Mean serum uric acid was 7.07 ± 1.25 mg/dL. During a median

SUBMITTER: Xiang S 

PROVIDER: S-EPMC6670192 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature