Usefulness of mycophenolate mofetil in Indian patients with C3 glomerulopathy.

ABSTRACT:

Background

C3 glomerulopathy (C3G) is a heterogeneous disease caused by alternative complement pathway abnormalities without any standardized treatment. An immunosuppressive agent, mycophenolate mofetil (MMF), has been recently shown to be useful in treating C3G, mainly in studies from the west. We report the clinical outcome of 17 Indian C3G patients treated with MMF with or without steroids.

Methods

The clinical and histology details of the C3G patients treated with MMF for at least 6 months with a follow-up of at least 12 months were retrieved from the medical records of our center.

Results

The median serum creatinine and proteinuria at presentation were 0.8 mg/dL and 3.7 g/day, respectively, with the majority (88.2%) presenting as nephrotic syndrome. The mean dose

SUBMITTER: Bharati J 

PROVIDER: S-EPMC6671524 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature