Ontology highlight
ABSTRACT:
SUBMITTER: Bonaz B
PROVIDER: S-EPMC6671930 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Bonaz Bruno B Sinniger Valérie V Pellissier Sonia S
Cold Spring Harbor perspectives in medicine 20190801 8
The vagus nerve, a key component of the cross-communication between the gut and the brain, is a major element of homeostasis sensing the "milieu intérieur" and boosting the nervous and endocrine responses to maintain the gastrointestinal health status. This nerve has anti-inflammatory properties regulating the gut through the activation of the hypothalamic-pituitary-adrenal axis and the release of cortisol and through a vagovagal reflex, which has an anti-tumor necrosis factor (TNF) effect calle ...[more]