Effect of low sperm quality on progeny: a study on zebrafish as model species.

ABSTRACT: Nowadays a decrease tendency in human sperm quality has been reported mainly in developed countries. Reproductive technologies have been very valuable in achieving successful pregnancies with low quality sperm samples. However, considering that spermatozoa molecular contribution is increasingly important in recent studies, it is crucial to study whether fertilization with low sperm quality could leave a molecular mark on progeny. This study explores the consequences that fertilization with low sperm quality may have on progeny, using zebrafish as a model. Good and bad breeders were established attending to sperm quality analyses and were individually tracked. Significant differences in fertilization and malformation rates were obtained in progenies between high and low quality sperm sample

SUBMITTER: Riesco MF 

PROVIDER: S-EPMC6671952 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature