Assessing Fever Frequency After Pediatric Live Attenuated Versus Inactivated Influenza Vaccination.

ABSTRACT:

Background

Some studies have found a higher frequency of fever with trivalent live attenuated influenza vaccine (LAIV) than with inactivated influenza vaccine (IIV), but quadrivalent LAIV has not been assessed. Understanding fever is important for safety reviews and for parents and providers. In addition, there have been only a limited number of studies in which text messaging was used for vaccine adverse-event (AE) surveillance.

Methods

We conducted a prospective observational study in 3 community clinics in New York City to assess post-influenza vaccination fever in 24- to 59-month-olds during the 2013-2014 season. Enrolled families of children who received quadrivalent LAIV (LAIV4) or IIV (trivalent IIV3 or quadrivalent IIV4) replied to text messages that assessed their t

SUBMITTER: Stockwell MS 

PROVIDER: S-EPMC6675416 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature