Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms.

ABSTRACT:

Objective

Alcoholism arises from combined effects of multiple biological factors including genetic and non-genetic causes with gene/environmental interaction. Intensive research and advanced genetic technology has generated a long list of genes and biomarkers involved in alcoholism neuropathology. These markers reflect complex overlapping and competing effects of possibly hundreds of genes which impact brain structure, function, biochemical alcohol processing, sensitivity and risk for dependence.

Method

We compiled a tabular list of clinically relevant genetic biomarkers for alcoholism targeting expression disturbances in the human brain through an extensive search of keywords related to alcoholism, alcohol abuse, and genetics from peer reviewed medical research articles and

SUBMITTER: Manzardo AM 

PROVIDER: S-EPMC6675570 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature