Aberrant regional homogeneity in post-traumatic stress disorder after traffic accident: A resting-state functional MRI study.

ABSTRACT:

Objectives

The present study explored the changes in spontaneous regional activity in post-traumatic stress disorder (PTSD) patients, who experienced severe traffic accidents.

Methods

20 drug-naive PTSD patients and 18 healthy control subjects were imaged using resting-state functional magnetic resonance imaging (rs-fMRI) and analyzed by the algorithm of regional homogeneity (ReHo).

Results

Compared to the healthy control group, the PTSD group showed decreased ReHo values in the right angular gyrus. In addition, a negative correlation was found between the activity level of the angular gyrus and the CAPS score.

Conclusion

The dysfunctions were found in the memory- and emotion-related areas, suggested a possible mechanism of memory dysregulation that might be re

SUBMITTER: Fu S 

PROVIDER: S-EPMC6676011 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature