Noninvasive cardiac output monitoring in a porcine model using the inspired sinewave technique: a proof-of-concept study.

ABSTRACT:

Background

Cardiac output (Q˙) monitoring can support the management of high-risk surgical patients, but the pulmonary artery catheterisation required by the current 'gold standard'-bolus thermodilution (Q˙_T)-has the potential to cause life-threatening complications. We present a novel noninvasive and fully automated method that uses the inspired sinewave technique to continuously monitor cardiac output (Q˙_IST).

Methods

Over successive breaths the inspired nitrous oxide (N₂O) concentration was forced to oscillate sinusoidally with a fixed mean (4%), amplitude (3%), and period (60 s). Q˙_IST was determined in a single-compartment tidal ventilation lung model that used the resulting amplitude/phase of the expired N₂O sinewa

SUBMITTER: Bruce RM 

PROVIDER: S-EPMC6676057 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature